相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation
Aaron Klug
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Inhibition of HIV-1 Replication by a Bis-Thiadiazolbenzene-1,2-Diamine That Chelates Zinc Ions from Retroviral Nucleocapsid Zinc Fingers
Christophe Pannecouque et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Zinc Finger Transcription Factor Zn3-SP1 Reactions with Cd2+
Rajendra Kothinti et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
Antiretroviral drugs
Erik De Clercq
CURRENT OPINION IN PHARMACOLOGY (2010)
Cysteine Oxidation Enhanced by Iron in Tristetraprolin, A Zinc Finger Peptide
Seung Jae Lee et al.
INORGANIC CHEMISTRY (2010)
Twenty-Six Years of Anti-HIV Drug Discovery: Where Do We Stand and Where Do We Go?
Youcef Mehellou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Cysteine proteases as targets for metal-based drugs
Simon P. Fricker
METALLOMICS (2010)
Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML
Xiao-Wei Zhang et al.
SCIENCE (2010)
Zinc Fingers as Biologic Redox Switches?
Klaus-D. Kroencke et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein
Volodymyr Shvadchak et al.
BIOCHIMIE (2009)
Coordination Dynamics of Zinc in Proteins
Wolfgang Maret et al.
CHEMICAL REVIEWS (2009)
Structural Adaptability of Zinc Binding Sites: Different Structures in Partially, Fully, and Heavy-Metal Loaded States
Uwe Heinz et al.
CHEMISTRY-A EUROPEAN JOURNAL (2009)
The Correlation of Cd-113 NMR and Cd-111m PAC Spectroscopies Provides a Powerful Approach for the Characterization of the Structure of Cd-II-Substituted Zn-II Proteins
Olga Iranzo et al.
CHEMISTRY-A EUROPEAN JOURNAL (2009)
Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs
Alberto Bindoli et al.
COORDINATION CHEMISTRY REVIEWS (2009)
RING Finger E3 Ubiquitin Ligases: Structure and Drug Discovery
Christos T. Chasapis et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Reactions of palladium and gold complexes with zinc-thiolate chelates using electrospray mass spectrometry and X-ray diffraction: molecular identification of [Pd(bme-dach)], [Au(bme-dach](+) and [ZnCl(bme-dach)](2)Pd
Queite A. de Paula et al.
DALTON TRANSACTIONS (2009)
PARP inhibitors in cancer therapy: Two modes of attack on the cancer cell widening the clinical applications
Yvette Drew et al.
DRUG RESISTANCE UPDATES (2009)
Towards Antitumor Active trans-Platinum Compounds
Sheena M. Aris et al.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2009)
Development of Five-Coordinate Zinc Mono- and Dithiolates as S-Donor Metalloligands: Formation of a Zn-W Coordination Polymer
Elky Almaraz et al.
INORGANIC CHEMISTRY (2009)
Biological Responses to Arsenic Compounds
Leonidas C. Platanias
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Novel targets for anti-retroviral therapy
Sanjay Bhattacharya et al.
JOURNAL OF INFECTION (2009)
Zinc finger proteins as templates for metal ion exchange: Substitution effects on the C-finger of HIV nucleocapsid NCp7 using M(chelate) species (M = Pt, Pd, Au)
Queite A. de Paula et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2009)
Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate
Allison S. Harney et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Current status of cadmium as an environmental health problem
Lars Jarup et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)
Historical perspectives on cadmium toxicology
Gunnar F. Nordberg
TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)
Comparison of cis and trans-platinum mononucleobase compounds with DNA and protein models
Joseph V. Strukl et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2008)
Interaction of trivalent antimony with a CCHC zinc finger domain: potential relevance to the mechanism of action of antimonial drugs
Cynthia Demicheli et al.
CHEMICAL COMMUNICATIONS (2008)
Monomethylarsonous acid destroys a tetrathiolate zinc finger much more efficiently than inorganic arsenite: Mechanistic considerations and consequences for DNA repair inhibition
Katarzyna Piatek et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Zinc metalloproteins as medicinal targets
A. I. Anzellotti et al.
CHEMICAL SOCIETY REVIEWS (2008)
New redesigned zinc-finger proteins: Design strategy and its application
Shigeru Negi et al.
CHEMISTRY-A EUROPEAN JOURNAL (2008)
Poly(ADP-ribose)polymerase-1 (PARP-1) in carcinogenesis:: Potential role of PARP inhibitors in cancer treatment
Andreina Peralta-Leal et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2008)
Metabolism and the Paradoxical Effects of Arsenic: Carcinogenesis and Anticancer
Xing Cui et al.
CURRENT MEDICINAL CHEMISTRY (2008)
DNA repair gets physical: Mapping an XPA-binding site on ERCC1
Deborah L. Croteau et al.
DNA REPAIR (2008)
Arsenic trioxide
Mark R. Litzow
EXPERT OPINION ON PHARMACOTHERAPY (2008)
The alkylation mechanism of zinc-bound thiolates depends upon the zinc ligands
Delphine Picot et al.
INORGANIC CHEMISTRY (2008)
Effects of Nucleobase Metalation on Frontier Molecular Orbitals: Potential Implications for π-Stacking Interactions with Tryptophan
Atilio I. Anzellotti et al.
INORGANIC CHEMISTRY (2008)
Spectroscopic evidence for the formation of goldfingers
Matthew A. Franzman et al.
INORGANIC CHEMISTRY (2008)
Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide
Yong Hwan Han et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
New insights into the chemical structure and composition of the pentavalent antimonial drugs, meglumine antimonate and sodium stibogluconate
Frederic Frezard et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2008)
Physical basis of structural and catalytic Zn-binding sites in proteins
Yu-ming Lee et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
How the HIV-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription
Sarah Bourbigot et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Thiolate bridging and metal exchange in adducts of a zinc finger model and PtII complexes:: Biomimetic studies of protein/Pt/DNA interactions
Elky Almaraz et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Targeting the Viral Nucleocapsid Protein in Anti-HIV-1 Therapy
Yves Mely et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif
Amit Arora et al.
RNA (2008)
The expanding role of arsenic in acute promyelocytic leukemia
Martin S. Tallman
SEMINARS IN HEMATOLOGY (2008)
Lead-poisoned zinc fingers: Quantum mechanical exploration of structure, coordination, and electronic excitations
Andrzej A. Jarzecki
INORGANIC CHEMISTRY (2007)
Quantification of cysteine oxidation in human estrogen receptor by mass spectrometry
Christian Atsriku et al.
ANALYTICAL CHEMISTRY (2007)
Sticky fingers: zinc-fingers as protein-recognition motifs
Roland Gamsjaeger et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
Paul A. Marks et al.
NATURE BIOTECHNOLOGY (2007)
Why does nature use zinc - a personal view
Heinrich Vahrenkamp
DALTON TRANSACTIONS (2007)
Zinc-promited alkyl transfer: a new role for zinc
James Penner-Hahn
CURRENT OPINION IN CHEMICAL BIOLOGY (2007)
Single DNA molecule stretching measures the activity of chemicals that target the HIV-1 nucleocapsid protein
Margareta Cruceanu et al.
ANALYTICAL BIOCHEMISTRY (2006)
Functional characterization of iron-substituted tristetraprolin-2D (TTP-2D, NUP475-2D): RNA binding affinity and selectivity
Robert C. diTargiani et al.
BIOCHEMISTRY (2006)
Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters
Lisa M. Miller Jenkins et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Structural basis of DNA recognition by p53 tetramers
Malka Kitayner et al.
MOLECULAR CELL (2006)
Targeting retroviral Zn finger-DNA interactions:: A small-molecule approach using the electrophilic nature of trans-platinum-nucleobase compounds
Atilio I. Anzellotti et al.
CHEMISTRY & BIOLOGY (2006)
Damage of zinc fingers in DNA repair proteins, a novel molecular mechanism in carcinogenesis
A Witkiewicz-Kucharczyk et al.
TOXICOLOGY LETTERS (2006)
The solution structure of the methylated form of the N-terminal 16-kDa domain of Escherichia coli Ada protein
H Takinowaki et al.
PROTEIN SCIENCE (2006)
Covalent and noncovalent interactions for [metal(dien)nucleobase]2+ complexes with L-tryptophan derivatives:: Formation of palladium-tryptophan species by nucleobase substitution under biologically relevant conditions
AI Anzellotti et al.
INORGANIC CHEMISTRY (2006)
Solution structure of p53 core domain:: Structural basis for its instability
JMP Cañadillas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Direct reversal of DNA alkylation damage
Y Mishina et al.
CHEMICAL REVIEWS (2006)
Donor atom preferences in substitution reactions of trans-platinum mononucleobase compounds: Implications for DNA-protein selectivity
A. Anzellotti et al.
INORGANICA CHIMICA ACTA (2006)
Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides
RJ Fisher et al.
NUCLEIC ACIDS RESEARCH (2006)
Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases
S Urig et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
GATA-1: One protein, many partners
JA Lowry et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)
Mechanisms of aurothiomalate -: Cys2His2 zinc finger interactions
JL Larabee et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2005)
Reactivity of zinc finger cysteines: Chemical modifications within labile zinc fingers in estrogen receptor
C Atsriku et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2005)
Intramolecular N-H•••S hydrogen bonding in the zinc thiolate complex [TmPh]ZnSCH2C(O)NHPh:: A mechanistic investigation of thiolate alkylation as probed by kinetics studies and by kinetic isotope effects
MM Morlok et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E-coli Ada
C He et al.
MOLECULAR CELL (2005)
Snail-regulated genes in malignant melanoma
S Kuphal et al.
MELANOMA RESEARCH (2005)
Reexamination of lead(II) coordination preferences in sulfur-rich sites: Implications for a critical mechanism of lead poisoning
JS Magyar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Structural perturbation of a C4 zinc-finger module by cis-diamminedichloroplatinum(II):: insights into the inhibition of transcription processes by the antitumor drug
RN Bose et al.
INORGANICA CHIMICA ACTA (2005)
Multiple modes of RNA recognition by zinc finger proteins
TMT Hall
CURRENT OPINION IN STRUCTURAL BIOLOGY (2005)
Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1NCp7 proteins
E Bombarda et al.
BIOCHEMISTRY (2005)
Discovery of small-molecule human immunodeficiency virus type 1 entry inhibitors that target the gp120-binding domain of CD4
QE Yang et al.
JOURNAL OF VIROLOGY (2005)
Spectroscopic and functional determination of the interaction of Pb2+ with GATA proteins
AB Ghering et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
H-bonding interactions and control of thiolate nucleophilicity and specificity in model complexes of zinc metalloproteins
JN Smith et al.
INORGANIC CHEMISTRY (2005)
Towards therapeutic applications of engineered zinc finger proteins
A Klug
FEBS LETTERS (2005)
Zinc finger proteins: Getting a grip on RNA
RS Brown
CURRENT OPINION IN STRUCTURAL BIOLOGY (2005)
Thiolate-bridged heterodinuclear platinum-zinc chelates as models for ternary platinum-DNA-protein complexes and zinc ejection from zinc fingers. Evidence from studies using ESI-mass spectrometry
Q Liu et al.
CHEMICAL COMMUNICATIONS (2005)
Zn-, Cd-, and Pb-transcription factor IIIA: properties, DNA binding, and comparison with TFIIIA-finger 3 metal complexes
ML Huang et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2004)
Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d
BP Hudson et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Synthetic analogues relevant to the structure and function of zinc enzymes
G Parkin
CHEMICAL REVIEWS (2004)
Entropy-enthalpy compensation in ionic interactions probed in a zinc finger peptide
CA Blasie et al.
BIOCHEMISTRY (2004)
Spectroscopic determination of the thermodynamics of cobalt and zinc binding to GATA proteins
AB Ghering et al.
BIOCHEMISTRY (2004)
Interaction of Cd2+ with Zn finger 3 of transcription factor IIIA:: Structures and binding to cognate DNA
D Krepkiy et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2004)
Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor
LH Wang et al.
NATURE MEDICINE (2004)
Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agent
M Kloster et al.
BIOCHEMISTRY (2004)
Why zinc fingers prefer zinc: Ligand-field symmetry and the hidden thermodynamics of metal ion selectivity
MJ Lachenmann et al.
BIOCHEMISTRY (2004)
Co(II) and Cd(II) substitute for Zn(II) in the zinc finger derived from the DNA repair protein XPA, demonstrating a variety of potential mechanisms of toxicity
E Kopera et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2004)
ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA
H Ishiguchi et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
The HIV-1 nucleocapsid zinc finger protein as a target of antiretroviral therapy
RA Musah
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2004)
Nickel carcinogenesis
Kazimierz S. Kasprzak et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2003)
Spectroscopic determination of the binding affinity of zinc to the DNA-binding domains of nuclear hormone receptors
JC Payne et al.
BIOCHEMISTRY (2003)
Modulation of DNA repair processes by arsenic and selenium compounds
A Hartwig et al.
TOXICOLOGY (2003)
Crystal structure of a zinc-finger - RNA complex reveals two modes of molecular recognition
D Lu et al.
NATURE (2003)
Trypanosoma cruzi poly-zinc finger protein:: a novel DNA/RNA-binding CCHC-zinc finger protein
JM Espinosa et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2003)
Cobalt-substituted zinc finger 3 of transcription factor IIIA:: Interactions with cognate DNA detected by 31P ENDOR spectroscopy
CJ Walsby et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Stress-induced activation of GATA-4 in cardiac muscle cells
YJ Suzuki
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Selective RNA binding by a single CCCH zinc-binding domain from Nup475 (Tristetraprolin)
SLJ Michel et al.
BIOCHEMISTRY (2003)
The role of chromatin damage in nickel-induced carcinogenesis. A review of recent developments
KS Kasprzak et al.
JOURNAL OF ENVIRONMENTAL MONITORING (2003)
Synthetic modeling of zinc thiolates: Quantitative assessment of hydrogen bonding in modulating sulfur alkylation rates
SJ Chiou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Converting the sacrificial DNA repair protein N-Ada into a catalytic methyl phosphotriester repair enzyme
C He et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Mechanism of nickel assault on the zinc finger of DNA repair protein XPA
WC Bal et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2003)
Control of thiolate nucleophilicity and specificity in zinc metalloproteins by hydrogen bonding: Lessons from model compound studies
JN Smith et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Sensing DNA damage by PARP-like fingers
S Petrucco
NUCLEIC ACIDS RESEARCH (2003)
Recent progress on the Ada response for inducible repair of DNA alkylation damage
B Sedgwick et al.
ONCOGENE (2002)
Inhibition of zinc finger protein-DNA interactions by sodium selenite
JL Larabee et al.
BIOCHEMICAL PHARMACOLOGY (2002)
Zinc fingers - Folds for many occasions
JM Matthews et al.
IUBMB LIFE (2002)
Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity
AG Stephen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Interference by toxic metal ions with zinc-dependent proteins involved in maintaining genomic stability
A Hartwig et al.
FOOD AND CHEMICAL TOXICOLOGY (2002)
Factors governing the protonation state of cysteines in proteins: An ab initio/CDM study
T Dudev et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
MJ Blanco et al.
ONCOGENE (2002)
Zn2+ binding properties of single-point mutants of the C-terminal zinc finger of the HIV-1 nucleocapsid protein:: Evidence of a critical role of cysteine 49 in Zn2+ dissociation
E Bombarda et al.
BIOCHEMISTRY (2002)
Interactions by carcinogenic metal compounds with DNA repair processes: toxicological implications
A Hartwig et al.
TOXICOLOGY LETTERS (2002)
Dynamics of mononuclear cadmium β-lactamase revealed by the combination of NMR and PAC spectroscopy
L Hemmingsen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Oxidation of zinc finger transcription factors: Physiological consequences
KA Webster et al.
ANTIOXIDANTS & REDOX SIGNALING (2001)
Zinc finger proteins as potential targets for toxic metal ions: Differential effects on structure and function
A Hartwig
ANTIOXIDANTS & REDOX SIGNALING (2001)
Mercuric ion inhibition of eukaryotic transcription factor binding to DNA
JS Rodgers et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Model reactions of Cr (VI) with DNA mediated by thiol species
D Krepkiy et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2001)
Catalytic selenols couple the redox cycles of metallothionein and glutathione
Y Chen et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
Herpes simplex virus type 1 entry is inhibited by the cobalt chelate complex CTC-96
JA Schwartz et al.
JOURNAL OF VIROLOGY (2001)
NMR identification of heavy metal-binding sites in a synthetic zinc finger peptide: Toxicological implications for the interactions of xenobiotic metals with zinc finger proteins
M Razmiafshari et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2001)
Glutathione-induced conversion of pentavalent antimony to trivalent antimony in meglumine antimoniate
F Frézard et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Reactivity of zinc finger cores: Analysis of protein packing and electrostatic screening
AT Maynard et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Zinc finger proteins: new insights into structural and functional diversity
JH Laity et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2001)
Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation
M Isalan et al.
BIOCHEMISTRY (2001)
Modulation of the chemical and biological properties of trans platinum complexes: monofunctional platinum complexes containing one nucleobase as potential antiviral chemotypes
DA Sartori et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2000)
Preferential oxidation of zinc finger 2 in estrogen receptor DNA-binding domain prevents dimerization and, hence, DNA binding
RM Whittal et al.
BIOCHEMISTRY (2000)
Role of the histidine residues of visna virus nucleocapsid protein in metal ion and DNA binding
DR Morcock et al.
FEBS LETTERS (2000)
Reactions of chromium(VI/V/IV) with bis(O-ethyl-L-cysteinato-N,S)zinc(II):: A model for the action of carcinogenic chromium on zinc-finger proteins
A Levina et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Utilization of a synthetic peptide as a tool to study the interaction of heavy metals with the zinc finger domain of proteins critical for gene expression in the developing brain
M Razmiafshari et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2000)
Cadmium mutagenicity and human nucleotide excision repair protein XPA:: CD, EXAFS and 1H/15N-NMR spectroscopic studies on the zinc(II)- and cadmium(II)-associated minimal DNA-binding domain (M98-F219)
GW Buchko et al.
CARCINOGENESIS (2000)