期刊
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
卷 20, 期 1, 页码 110-114出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/gme.0b013e31825a27ab
关键词
Cognitive function; Oophorectomy; Osteoporosis; Ovarian cancer prevention; Sexual function
资金
- Eunice Kennedy Shriver National Institute of Child Health and Human Development [K12 HD047018]
Ovarian cancer remains the fifth deadliest cancer among women because of its early asymptomatic nature and lack of efficacious screening methods, leading to frequent late-stage diagnosis. Elective oophorectomy is an option for women undergoing benign hysterectomy as a means of reducing their ovarian cancer risk. Benefits also include reduced risk of repeat surgical operation due to adnexal masses and reduced anxiety related to perceived risk of ovarian and breast cancer. The potential negative side effects of elective oophorectomy, such as decreased cognition and sexual function and increased risk of osteoporosis and cardiac mortality, offer support for ovarian conservation. The implications of this elective procedure and the possible consequences without it require physicians to review the pros and cons with patients in light of the patient's individual circumstances and ovarian cancer risk.
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