期刊
MEMORIAS DO INSTITUTO OSWALDO CRUZ
卷 109, 期 6, 页码 820-823出版社
FUNDACO OSWALDO CRUZ
DOI: 10.1590/0074-0276140108
关键词
Mayaro virus; dengue virus 4; Mato Grosso
资金
- CNPq
- CAPES
- UFMT
Mayaro virus (MAYV) is frequently reported in Pan-Amazonia. The aim of this study was to investigate the circulation of alphaviruses during a dengue outbreak in the state of Mato Grosso, Brazil. Serum samples from dengue-suspected patients were subjected to multiplex semi-nested reverse transcriptase polymerase chain reaction for 11 flaviviruses and five alphaviruses, to nucleotide sequencing and to viral isolation. MAYV was detected in 15 (2.5%) of 604 patients. Twelve were co-infected with dengue virus 4, which was isolated from 10 patients. The molecular detection of MAYV in dengue-suspected patients suggests that other arboviruses may be silently circulating during dengue outbreaks in Brazil.
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