期刊
MEMORIAS DO INSTITUTO OSWALDO CRUZ
卷 105, 期 7, 页码 942-944出版社
FUNDACO OSWALDO CRUZ
DOI: 10.1590/S0074-02762010000700020
关键词
eosinophilia; diagnosis; meningitis; angiostrongyliasis; Angiostrongylus cantonensis
资金
- Research and Diagnostic Center for Emerging Infectious Disease, Khon Kaen University
- Office of Higher Education Commission/Ministry of Education
The diagnosis of meningitic angiostrongyliasis (MA) is based on clinical criteria. A lumbar puncture is used as a diagnostic tool, but it is an invasive procedure. The blood eosinophil levels are also assessed and used in the diagnosis of this disease. We enrolled 47 patients with serologically proven MA and 131 controls with intestinal parasite infections. An absolute eosinophil count model was found to be the best marker for MA. An eosinophil count of more than 798 cells led to sensitivity, specificity, positive predictive and negative predictive values of 76.6%, 80.2%, 58.1% and 90.5%, respectively. These data support the use of testing for high blood eosinophil levels as a diagnostic tool for MA in individuals that are at risk for this disease.
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