期刊
MEMORIAS DO INSTITUTO OSWALDO CRUZ
卷 105, 期 8, 页码 957-964出版社
FUNDACO OSWALDO CRUZ
DOI: 10.1590/S0074-02762010000800002
关键词
Aedes aegypti; Wolbachia; dengue; risk assessment; safety; biological control
资金
- FNIH/Grand Challenges in Global Health Initiative/Bill
- Melinda Gates Foundation/NHMRC
Mosquito-borne diseases such as dengue fever, chikungunya or malaria affect millions of people each year and control solutions are urgently needed. An international research program is currently being developed that relies on the introduction of the bacterial endosymbiont Wolbachia pipientis into Aedes aegypti to control dengue transmission. In order to prepare for open-field testing releases of Wolbachia-infected mosquitoes, an intensive social research and community engagement program was undertaken in Cairns, Northern Australia. The most common concern expressed by the diverse range of community members and stakeholders surveyed was the necessity of assuring the safety of the proposed approach for humans, animals and the environment. To address these concerns a series of safety experiments were undertaken. We report in this paper on the experimental data obtained, discuss the limitations of experimental risk assessment and focus on the necessity of including community concerns in scientific research.
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