期刊
MEMORIAS DO INSTITUTO OSWALDO CRUZ
卷 103, 期 7, 页码 650-652出版社
FUNDACO OSWALDO CRUZ
DOI: 10.1590/S0074-02762008000700004
关键词
antibacterial; cytotoxicity; medicinal plants
资金
- Commission of Higher Education [CHE/1/26/1/4,PI]
Seven medicinal plant extracts traditionally used in Kenya, mainly for management of infectious conditions, were chosen and screened for their antibacterial activity against Gram-negative (Pseudomonas aeruginosa and Escherichia coli) and Gram-positive (Bacillus cereus and Staphylococcus aureus) bacteria. Antibacterial activity was tested using the broth dilution method. Harrisonia abyssinica and Terminalia kilimandscharica extracts showed significant activity against Gram+ and Gram-bacteria. The methanolic extracts of T. kilimandscharica bark and H. abyssinica bark and leaves showed minimum inhibitory activity against all tested bacteria, with minimal inhibitory concentrations ranging from 25-150 mg/mL. Ajuga remota and Amaranthus hybridus, which are lethal to brine shrimp nauplii, showed significantly lower antibacterial activity than those that were relatively non-toxic.
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