期刊
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
卷 41, 期 2, 页码 113-124出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1068162015020041
关键词
albumin; esterases; thiol peroxidase; organophosphorus compounds; molecular docking; enzymes
资金
- Russian Foundation for Basic Research [13-04-01728a]
Albumin molecules, unlike molecules of many other plasma proteins, are not covered with a carbohydrate shell. Albumin plays a crucial role in maintaining colloid osmotic blood pressure and can bind and transport various endogenous and exogenous molecules. The enzymatic activity of albumin, the existence and the role of which most researchers are still skeptical to accept, is our main interest. In this review, a history of the issue is traced, with particular attention paid to the esterase activity of albumin. The kinetic and thermodynamic characteristics of the interaction of albumin with some substrates are adduced, and the possibility of attributing albumin to certain groups of Enzyme Nomenclature is considered.
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