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Inhibitors and Antagonists of Bacterial Quorum Sensing

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MEDICINAL RESEARCH REVIEWS
卷 29, 期 1, 页码 65-124

出版社

WILEY
DOI: 10.1002/med.20145

关键词

quorum sensing; inhibitors; autoinducers; antagonists

资金

  1. Georgia Research Alliance
  2. Georgia Cancer Coalition
  3. Molecular Basis of Disease Program at GSU

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Bacteria can regulate community-wide behaviors including biofilm formation, virulence, conjugation, sporulation, and swarming motility through a process called quorum sensing. Inhibitors and antagonists of bacterial quorum sensing are important research tools and potential therapeutic agents. In this review, we have summarized recent developments in this area. (C) 2008 Wiley Periodicals, Inc. Med Res Rev, 29, No. 1, 65-124, 2009

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