相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Synthesis and in vitro characterization of some benzothiazole- and benzofuranone-derivatives for quantification of fibrillar aggregates and inhibition of amyloid-mediated peroxidase activity
Seyyed Abolghasem Ghadami et al.
MEDICINAL CHEMISTRY RESEARCH (2013)
New molecular scaffolds for the design of Alzheimer's acetylcholinesterase inhibitors identified using ligand- and receptor-based virtual screening
Nitin Chitranshi et al.
MEDICINAL CHEMISTRY RESEARCH (2013)
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents
Stefano Rizzo et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment
A. Minarini et al.
NEUROPHARMACOLOGY (2012)
Multi-Target-Directed Ligands in Alzheimer's Disease Treatment
M. Bajda et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors
Huang Tang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Clicked tacrine conjugates as acetylcholinesterase and beta-amyloid directed compounds
Myriam Ouberai et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2011)
Update on the Pharmacological Treatment of Alzheimer's Disease
Fadi Massoud et al.
CURRENT NEUROPHARMACOLOGY (2010)
Novel Tacrine-8-Hydroxyquinoline Hybrids as Multifunctional Agents for the Treatment of Alzheimer's Disease, with Neuroprotective, Cholinergic, Antioxidant, and Copper-Complexing Properties
Maria Isabel Fernandez-Bachiller et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
John C. O'Leary et al.
MOLECULAR NEURODEGENERATION (2010)
Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and β-secretase
Yiping Zhu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Designing Multiple Ligands - Medicinal Chemistry Strategies and Challenges
Richard Morphy et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Mediators of tau phosphorylation in the pathogenesis of Alzheimer's disease
Diane P. Hanger et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2009)
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
Diane P. Hanger et al.
TRENDS IN MOLECULAR MEDICINE (2009)
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces β-amyloid generation by directly inhibiting BACE-1 activity
Hongjun Fu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Further Investigation on the Inner Spacer
Vincenzo Tumiatti et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Inhibition of acetylcholinesterase, β-amyloid aggregation, and NMDA receptors in Alzheimer's disease:: A promising direction for the multi-target-directed ligands gold rush
Michela Rosini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Multi-target-directed ligands to combat neurodegenerative diseases
Andrea Cavalli et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents
Jialie Luo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Aβ interaction
Yilin Yan et al.
BIOCHEMISTRY (2007)
A small molecule targeting the multifactorial nature of Alzheimer's disease
Andrea Cavalli et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Search for dual function inhibitors for Alzheimer's disease:: Synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Aβ fibril formation inhibition capacity
P Kapková et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Novel dimeric acetylcholinesterase inhibitor bis(7)-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
WM Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
S Taniguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives
S Darvesh et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease
J Sterling et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Homodimeric tacrine congeners as acetylcholinesterase inhibitors
MK Hu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)