Biological importance of imidazole nucleus in the new millennium

Imidazole nucleus is a constituent of many bioactive heterocyclic compounds that are of wide interest because of their diverse biological and clinical applications. This created interest in researchers to synthesize variety of imidazole derivatives and to screen them for their various biological activities viz. anti-cancer, anti-viral, antiHIV, anti-protozoal, anti-mycobacterial, anti-inflammatory, analgesic, anxiolytic, as well anti-diabetic activities.