期刊
MEDICINAL CHEMISTRY RESEARCH
卷 20, 期 5, 页码 542-548出版社
SPRINGER BIRKHAUSER
DOI: 10.1007/s00044-010-9348-8
关键词
Pyran; Triazolidine; Antibacterial activity; Antifungal activity
资金
- Council of Scientific and Industrial Research, New Delhi, India
Some new 7,9-diaryl-1,2,4-triaza-8-oxa-spiro[4.5]-decan-3-thiones has been synthesised and their antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi, and antifungal activity against Candida albicans, Rhizopus sp., Aspergillus flavus and Aspergillus niger were examined. Compounds 14 and 15 against E. coli and S. typhi showed marked antibacterial activity. Similarly, compounds 13 and 15 against Rhizopus sp. and 13 and 14 against A. flavus exerted significant antifungal activities.
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