期刊
MEDICAL PHYSICS
卷 39, 期 8, 页码 5194-5203出版社
WILEY
DOI: 10.1118/1.4738963
关键词
dosimetry; Monte Carlo; linear accelerators; radiation therapy; flattening filter; flattening filter free
资金
- Strategic Research Area Medical Technology at the Norwegian University of Science and Technology
Purpose: To compare dosimetric characteristics of 6 MV photon fields originating from a linear accelerator operating with (FF) and without (FFF) a flattening-filter. The main objective is to establish a FFF model that results in similar depth-dose and build-up profiles as the original FF model, and subsequently estimate and compare out-of-field dose distributions. Methods: The EGSnrc Monte Carlo user codes BEAMnrc and DOSXYZnrc are used for photon beam simulations of an Elekta linear accelerator and dose calculations in a water phantom, respectively. Three beam models were analyzed: (1) the conventional linear accelerator with the flattening-filter in place and incident electron energy 6.45 MeV (FF 6.45 MeV), (2) similar flattening-filter-free model (FFF 6.45 MeV), and (3) as (2) but with increased electron energy (FFF 8.0 MeV). The field size 5 x 5 cm(2) was used for characterization of dose output, depth dose profiles, and photon spectrum. The field size 40 x 40 cm(2) was used for characterization of cross-field photon energy, photon fluence, and dose distributions. Out-of-field dose distributions were analyzed in both in-plane and cross-plane directions for 5 x 5 cm(2) and 10 x 10 cm(2) fields. Results: Comparable depth dose distributions, including the build-up region, for FF and FFF fields were achieved by increasing the electron energy from 6.45 MeV to 8.0 MeV for the FFF beam. The Fit beams result in reduced out-of-field dose compared to the FF beam: the reduction was most apparent in the cross-plane direction and more pronounced by the FFF 8.0 MeV beam compared to the FFF 6.45 MeV beam. Differences in out-of-field dose due to direction (in-plane vs cross-plane) were up to 40% for the FF beam; this effect was significantly reduced for the FFF beams. As the flattening-filter is a major source of contaminating electrons, superficial out-of-field dose was expected, and was found to be, reduced for 14414 beams. Conclusions: The build-up and depth-dose characteristics of a conventional 6 MV beam can be maintained when changing to a flattening-filter-free modality by increasing the incident electron energy from 6.45 MeV to 8.0 MeV. This will at the same time reduce the out-of-field dose for regions up to 20 cm from the central axis by 10%-30% compared to the original FF situation. (C) 2012 American Association of Physicists in Medicine. [http://dx.doi.org/10.1118/1.4738963]
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