相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Overexpression of TGF-β1 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cells
Yong Il Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
TGFβ signaling in cartilage development and maintenance
Weiguang Wang et al.
BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2014)
CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
Louise N. Reynard et al.
HUMAN GENETICS (2014)
Systems genetics approaches to understand complex traits
Mete Civelek et al.
NATURE REVIEWS GENETICS (2014)
SMAD3 Is Associated with the Total Burden of Radiographic Osteoarthritis: The Chingford Study
Erfan Aref-Eshghi et al.
PLOS ONE (2014)
Thoracic Aortic Aneurysm in Infancy in Aneurysms-Osteoarthritis Syndrome Due to a Novel SMAD3 Mutation: Further Delineation of the Phenotype
Anita Wischmeijer et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2013)
Toward Regeneration of Articular Cartilage
Masahiro Iwamoto et al.
BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2013)
Advances in osteoarthritis genetics
Kalliope Panoutsopoulou et al.
JOURNAL OF MEDICAL GENETICS (2013)
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
Gehua Zhen et al.
NATURE MEDICINE (2013)
NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis
Ginette Tardif et al.
ARTHRITIS RESEARCH & THERAPY (2013)
Development of the Endochondral Skeleton
Fanxin Long et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Chondrocyte-intrinsic Smad3 represses runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis
Carol G. Chen et al.
ARTHRITIS AND RHEUMATISM (2012)
Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily
Andrew P. Hinck
FEBS LETTERS (2012)
Phenotypic spectrum of the SMAD3-related aneurysms-osteoarthritis syndrome
Ingrid M. B. H. van de Laar et al.
JOURNAL OF MEDICAL GENETICS (2012)
TGFβ signalling in context
Joan Massague
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
TGF-Beta Induced Erk Phosphorylation of Smad Linker Region Regulates Smad Signaling
Chris Hough et al.
PLOS ONE (2012)
Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes
Ioanna Papathanasiou et al.
ARTHRITIS RESEARCH & THERAPY (2012)
Exome Sequencing Identifies SMAD3 Mutations as a Cause of Familial Thoracic Aortic Aneurysm and Dissection With Intracranial and Other Arterial Aneurysms
Ellen S. Regalado et al.
CIRCULATION RESEARCH (2011)
Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation
Louise N. Reynard et al.
HUMAN MOLECULAR GENETICS (2011)
Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis
Ingrid M. B. H. van de laar et al.
NATURE GENETICS (2011)
Signaling Pathways in Human Skeletal Dysplasias
Dustin Baldridge et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 11 (2010)
Genetic Variation in the SMAD3 Gene Is Associated With Hip and Knee Osteoarthritis
Ana M. Valdes et al.
ARTHRITIS AND RHEUMATISM (2010)
Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers
Logan C. Walker et al.
BREAST CANCER RESEARCH (2010)
Differential upregulation of the three transforming growth factor beta isoforms in human osteoarthritic cartilage
M. Pombo-Suarez et al.
ANNALS OF THE RHEUMATIC DISEASES (2009)
Smad signaling in skeletal development and regeneration
Buer Song et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation
Kelsey N. Retting et al.
DEVELOPMENT (2009)
Critical roles of the TGF-β type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development
Tomoya Matsunobu et al.
DEVELOPMENTAL BIOLOGY (2009)
Smad3 activates the Sox9-dependent transcription on chromatin
Takayuki Furumatsu et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice
Esmeralda N. Blaney Davidson et al.
JOURNAL OF IMMUNOLOGY (2009)
Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation
Tilo Dehne et al.
ARTHRITIS RESEARCH & THERAPY (2009)
Association of the asporin D14 allele with lumbar-disc degeneration in Asians
You-Qiang Song et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Induction of an Osteoarthritis-like Phenotype and Degradation of Phosphorylated Smad3 by Smurf2 in Transgenic Mice
Qiuqian Wu et al.
ARTHRITIS AND RHEUMATISM (2008)
Modulation of TGF-β signaling by proinflammatory cytokines in articular chondrocytes
J. A. Roman-Blas et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis
Jiang Wu et al.
ARTHRITIS AND RHEUMATISM (2007)
Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints
Hwa-Seon Seo et al.
DEVELOPMENTAL BIOLOGY (2007)
An SNP in the 5′-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage
Lorraine Southam et al.
HUMAN MOLECULAR GENETICS (2007)
A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis
Yoshinari Miyamoto et al.
NATURE GENETICS (2007)
Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study
G. Zhai et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells
Lee Tuddenham et al.
FEBS LETTERS (2006)
Activation of Smad signaling enhances collagenase-3 (MMP-13) expression and invasion of head and neck squamous carcinoma cells
SK Leivonen et al.
ONCOGENE (2006)
Smad3 knock-out mice as a useful model to study intestinal fibrogenesis
Giuliana Zanninelli et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2006)
Transforming growth factor-beta 2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E-2 production
EV Tchetina et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese
Qing Jiang et al.
JOURNAL OF HUMAN GENETICS (2006)
Transforming growth factor-β activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2
MC Wilkes et al.
CANCER RESEARCH (2005)
Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population
Z Mustafa et al.
ARTHRITIS AND RHEUMATISM (2005)
A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis
VK Srikanth et al.
OSTEOARTHRITIS AND CARTILAGE (2005)
Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2
P Seemann et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Smad4 is required for the normal organization of the cartilage growth plate
JH Zhang et al.
DEVELOPMENTAL BIOLOGY (2005)
Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo
BS Yoon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Immunohistochemical analysis of transforming growth factor beta isoforms and their receptors in human cartilage from normal and osteoarthritic femoral heads
MP Verdier et al.
RHEUMATOLOGY INTERNATIONAL (2005)
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis
H Kizawa et al.
NATURE GENETICS (2005)
Transforming growth factor-β1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the smad and MAPK signaling pathways and their components, Smad2 and Runx2
N Selvamurugan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Conditional deletion of the TGF-β type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones
MO Baffi et al.
DEVELOPMENTAL BIOLOGY (2004)
Transforming growth factor-β1 gene polymorphisms and bone turnover, bone mineral density and fracture risk in southern Chinese women
HHL Lau et al.
CALCIFIED TISSUE INTERNATIONAL (2004)
An update on the pathogenesis and epidemiology of osteoarthritis
DT Felson
RADIOLOGIC CLINICS OF NORTH AMERICA (2004)
Transforming growth factor-β-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogenactivated protein kinase and Wnt signaling cross-talk
R Tuli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mechanisms of TGF-β signaling from cell membrane to the nucleus
YG Shi et al.
CELL (2003)
Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis:: Sox genes and BMP signaling
J Chimal-Monroy et al.
DEVELOPMENTAL BIOLOGY (2003)
Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3
MC Wilkes et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Transcriptional activation of collagenase-3 by transforming growth factor-β1 is via MAPK and Smad pathways in human breast cancer cells
N Selvamurugan et al.
FEBS LETTERS (2002)
Smad3 mediates transforming growth factor-β-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts -: Evidence for cross-talk between Smad3 and p38 signaling pathways
SK Leivonen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Inhibition of endogenous TGF-β during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair
A Scharstuhl et al.
JOURNAL OF IMMUNOLOGY (2002)
Internalization-dependent and -independent requirements for transforming growth factor β receptor signaling via the Smad pathway
SG Penheiter et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Can altered production of interleukin-1β, interleukin-6, transforming growth factor-β and prostaglandin E2 by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients
F Massicotte et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
Association of transforming growth factor-β1 (TGFβ1) T29→C gene polymorphism with bone mineral density (BMD), changes in BMD, and serum concentrations of TGF-β1 in a population-based sample of postmenopausal German women
V Hinke et al.
CALCIFIED TISSUE INTERNATIONAL (2001)
Chondrogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components
F Barry et al.
EXPERIMENTAL CELL RESEARCH (2001)
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
WM Bi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
TGF-β/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage
X Yang et al.
JOURNAL OF CELL BIOLOGY (2001)
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation
AC Bakker et al.
OSTEOARTHRITIS AND CARTILAGE (2001)
How cells read TGF-β signals
J Massagué
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2000)
TGFβ signaling in growth control, cancer, and heritable disorders
J Massagué et al.
CELL (2000)
Domain-specific mutations in TGFB1 result in Camurati-Engelmann disease
A Kinoshita et al.
NATURE GENETICS (2000)
Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections
HM van Beuningen et al.
OSTEOARTHRITIS AND CARTILAGE (2000)
分享论文
