期刊
MEDICAL PHYSICS
卷 35, 期 10, 页码 4524-4529出版社
WILEY
DOI: 10.1118/1.2977534
关键词
photoacoustic imaging; internal organ; thoracic cavity; heart; kidney
资金
- National Institutes of Health [R01 EB000712, R01 NS46214]
The internal organs of rats and rabbits were clearly imaged noninvasively using a deeply penetrating reflection-mode photoacoustic imaging system. This imaging system had previously been found to provide an imaging depth limit of similar to 38 mm. In the thoracic cavity, major blood vessels connecting to the heart were imaged, and the right atrium was imaged as deeply as similar to 8 mm. In the abdominal cavities, the kidney and vena cava inferior were also imaged in situ. The vena cava inferior similar to 13.7 mm deep was imaged. The kidney of a New Zealand white rabbit was also imaged. This study shows the deep internal organ imaging capability of the system in animals. This technology can potentially be used to study tumors in internal organs, and be adapted to clinical diagnosis. (C) 2008 American Association of Physicists in Medicine.
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