期刊
RHEUMATOLOGY
卷 55, 期 7, 页码 1159-1171出版社
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/kev366
关键词
Takayasu arteritis; large vessel vasculitis; outcome measure; disease assessment
类别
资金
- Japan College of Rheumatology and Shimoshizu Hospital, National Hospital Organization
- Cambridge Biomedical Research Centre
Takayasu arteritis (TAK) is a systemic granulomatous large-vessel vasculitis with a phenotype that overlaps with GCA and defined by the 1993 and 2012 Chapel Hill Consensus Conference statements. However, the diagnosis of TAK is often delayed since TAK patients may be asymptomatic or have non-specific symptoms. Once a diagnosis is made, it is difficult to judge remission or recurrence since there are no reliable assessment tools. With the availability of newer agents, such as cytokine blockade, which are being evaluated in GCA, there is the potential for real advances in TAK patient management. Without reliable assessment tools it will be difficult to introduce newer agents in an organized way or to optimally benefit patients in the future. In this article we review the use and performance of disease indicators in TAK clinical trials as a basis for the further development of assessment tools for this disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据