期刊
MEDICAL ONCOLOGY
卷 31, 期 1, 页码 -出版社
HUMANA PRESS INC
DOI: 10.1007/s12032-013-0800-8
关键词
Hodgkin lymphoma; Chronic lymphocytic leukemia; Histological transformation; Trephine biopsy
类别
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is the most common form of leukemia affecting adults in Europe and North America. Large B-cell lymphoma known as Richter's syndrome (RS) may develop approximately in 3-15 % patients. Furthermore, other hematological malignancies may also occur as RS variants, among them-Hodgkin lymphoma (HL). CLL/SLL transformation into HL is observed in about 0.5 % of patients, and till now, fewer than 100 cases have been reported in the medical literature. We present two cases of HL transformation of CLL/SLL and review the previously published literature.
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