期刊
MEDICAL ONCOLOGY
卷 29, 期 3, 页码 1515-1517出版社
HUMANA PRESS INC
DOI: 10.1007/s12032-011-0059-x
关键词
Breast cancer; HPV; Invasive ductal carcinoma
类别
资金
- Fondos Sectoriales from Consejo Nacional de Ciencia y Tecnologia (CONACyT-Mexico) [69,719, 87,244]
- IMSS [38-HO-04]
The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.
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