期刊
MEDICAL MYCOLOGY
卷 49, 期 7, 页码 714-723出版社
OXFORD UNIV PRESS
DOI: 10.3109/13693786.2011.568975
关键词
Mucor irregularis; Rhizomucor irregularis; mucormycosis; zygomycosis; heterothallism; zygospore
This study reports on the discovery of heterothallic mating in Mucor irregularis (formerly Rhizomucor variabilis var. variabilis) and it extends the range of this species from Asia to the United States. We report on a case of primary cutaneous mucormycosis, involving the forearms of a cotton farmer from North Carolina, in which the infection was cured using amphotericin B therapy. Intraspecific crosses between the North Carolina strain DUMC 150.04 and M. irregularis CBS 103.93, the ex-type strain of R. variabilis var. variabilis from China, resulted in the formation of abundant fertile zygospores. By way of contrast, interspecific crosses between the North Carolina isolate and the ex-neotype strain of M. hiemalis NRRL 3624 resulted in the formation of putative azygospores by M. irregularis DUMC 150.04.
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