4.4 Article

Modelling wall shear stress in small arteries using method: influence of the endothelial wall profile

期刊

MEDICAL ENGINEERING & PHYSICS
卷 33, 期 7, 页码 832-839

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.medengphy.2011.03.009

关键词

Arterial endothelium; Blood flow; Wall shear stress; Lattice Boltzmann methods LBM

资金

  1. BBSRC [BB/F013744/1] Funding Source: UKRI
  2. Biotechnology and Biological Sciences Research Council [BB/F013744/1] Funding Source: researchfish
  3. Biotechnology and Biological Sciences Research Council [BB/F013744/1] Funding Source: Medline

向作者/读者索取更多资源

In order to address the problem of blood flow over the endothelium in small arteries, the near-endothelial region is here studied in more detail. The method used is a finite-volume discretisation of a Lattice Boltzmann equation over unstructured grids, named unstructured lattice Boltzmann equation (ULBE). It is a new scheme based on the idea of placing the unknown fields at the nodes of the mesh and evolving them based on the fluxes crossing the surfaces of the corresponding control volumes. The study shows a significant variation and a high sensitivity of wall shear stress to the height of the endothelium corrugation and the presence of erythrocytes. The latter were modelled as deformable, viscous particles within a fluid continuum. (C) 2011 IPEM. Published by Elsevier Ltd. All rights reserved.

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