期刊
MEDICAL CLINICS OF NORTH AMERICA
卷 93, 期 1, 页码 25-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mcna.2008.09.006
关键词
Osteoarthritis; Bone; Cartilage; Biomechanics; Remodeling
Much of the attention in developing diagnostic tools and therapeutic interventions for the management of osteoarthritis (OA) has focused on the preservation or repair of articular cartilage. It is clear that all of the joint components, including the ligaments, tendons, capsule, synovial lining, and periarticular bone, undergo structural and functional alterations during the course of OA progression. This article focuses on the specific skeletal features of OA and the putative mechanisms involved in their pathogenesis.
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