3.9 Article

Two-domain DNA strand displacement

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MATHEMATICAL STRUCTURES IN COMPUTER SCIENCE
卷 23, 期 2, 页码 247-271

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CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0960129512000102

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We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal processing gates based on these structures, and show that these systems are amenable to formalisation and mechanical verification.

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