期刊
MATHEMATICAL METHODS IN THE APPLIED SCIENCES
卷 39, 期 16, 页码 4671-4679出版社
WILEY-BLACKWELL
DOI: 10.1002/mma.3319
关键词
dengue; vectorial capacity; seasonality; basic reproduction number; sensitivity analysis; optimal control
资金
- Portuguese funds through Portuguese Foundation for Science and Technology (FCT)
- Center for Research and Development in Mathematics and Applications (CIDMA) [PEst-OE/MAT/UI4106/2014]
- ALGORITMI RD Center
- [PEST-OE/EEI/UI0319/2014]
- Fundação para a Ciência e a Tecnologia [PEst-OE/MAT/UI4106/2014, PEst-OE/EEI/UI0319/2014] Funding Source: FCT
Dengue is a vector-borne disease transmitted from an infected human to an Aedes mosquito, during a blood meal. Dengue is still a major public health problem. A model for the disease transmission is presented, composed by human and mosquitoes compartments. The aim is to simulate the effects of seasonality, on the vectorial capacity and, consequently, on the disease development. Using entomological information about the mosquito behavior under different temperatures and rainfall, simulations are carried out, and the repercussions analyzed. The basic reproduction number of the model is given, as well as a sensitivity analysis of model's parameters. Finally, an optimal control problem is proposed and solved, illustrating the difficulty of making a trade-off between reduction of infected individuals and costs with insecticide. Copyright (c) 2014 John Wiley & Sons, Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据