期刊
MATHEMATICAL BIOSCIENCES
卷 227, 期 2, 页码 117-124出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mbs.2010.07.001
关键词
Micro-vascular blood flow; Networks; Bistability; Nonlinear dynamics
资金
- NSF
- Dean of Faculty at Olin College
We use a simple model of micro-vascular blood flow to explore conditions that give rise to multiple equilibrium states in a three-node micro-vascular network. The model accounts for two primary theological effects: the Fahraeus-Lindqvist effect, which describes the apparent viscosity of blood in a vessel, and the plasma skimming effect, which governs the separation of red blood cells at diverging nodes. We show that multiple equilibrium states are possible, and we use our analytical and computational tools to design an experiment for validation. (C) 2010 Elsevier Inc. All rights reserved.
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