4.5 Article

Cognitive function and health-related quality of life four years after cardiac arrest

期刊

RESUSCITATION
卷 89, 期 -, 页码 13-18

出版社

ELSEVIER IRELAND LTD
DOI: 10.1016/j.resuscitation.2014.12.021

关键词

Cardiac arrest; Cognition disorders; CANTAB; Neuropsychological tests; Quality of life; Treatment outcome

资金

  1. Laerdal Foundation for Acute Medicine [2012/2869]
  2. University of Bergen

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Aim: Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related quality of life four years after cardiac arrest. Methods: Thirty cardiac arrest survivors over the age of 18 in cerebral performance category 1 or 2 on hospital discharge completed the EQ-5D-5L and HADS questionnaires prior to cognitive testing using the Cambridge Neuropsychological Test Automated Battery. The results were compared with population norms. Results: Twenty-nine per cent of patients were cognitively impaired. The pattern of cognitive impairment reflects dysfunction in the medial temporal lobe, with impaired short-time memory and executive function slightly but distinctly affected. There was a significant reduction in quality of life on the EQ-VAS, but not on the EQ index. Conclusion: Cognitive impairment four years after cardiac arrest affected more than one quarter of the patients. Short-term memory was predominantly affected. (C) 2015 The Authors. Published by Elsevier Ireland Ltd.

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