期刊
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
卷 33, 期 4, 页码 2197-2202出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2013.01.039
关键词
Streptococcus mutans; Silver nanoparticles; Adherence inhibition; Inhibitory effect; Antibacterial effect; Dental enamel
资金
- Fondo de Apoyo a la Investigacion [FAI C12-FAI-03-42.42]
- Programa de Mejoramiento del Profesorado (PROMEP)
- Consejo Nacional de Ciencia y Tecnologia [CONACYT CB-169020]
The aim of this ex vivo study was to evaluate the adherence capacity of Streptococcus mutans after being exposed to three different sizes of silver nanoparticles on healthy human dental enamel. Three different sizes of silver nanoparticles (9.3, 21.3 and 98 nm) were prepared, characterized and an adherence testing was performed to evaluate their anti-adherence activity on a reference strain of S. mutans on healthy dental enamel surfaces. Colony-Forming Unit count was made for adherence test and light microscopy, atomic force microscopy and scanning electron microscopy were used to compare qualitative characteristics of S. mutans. 9.3 nm and 21.3 nm groups did not show differences between them but statistical differences were found when 9.3 nm and 21.3 nm groups were compared with 98 nm and negative control groups (p<0.05). Microscopy analysis shows a better inhibition of S. mutans adherence in 93 nm and 21.3 nm groups than the 98 nm group when compared with control group. Silver nanoparticles showed an adherence inhibition on S. mutans and the anti-adherence capacity was better when silver nanoparticles were smaller. (C) 2013 Elsevier B.V. All rights reserved.
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