4.3 Article

Microstructure, mechanical property, bio-corrosion and cytotoxicity evaluations of Mg/HA composites

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ELSEVIER
DOI: 10.1016/j.msec.2010.03.016

关键词

Mg/HA composite; Microstructure; Mechanical property; Corrosion; Cytotoxicity

资金

  1. foundation of Key Laboratory for Advanced Materials Processing Technology, Ministry of Education [2008001]
  2. National Natural Science Foundation of China [30670560]
  3. Science and Technology Project of Guangdong Province [2008A030102006]
  4. Shenzhen Industry-Education-Research Cooperation
  5. Program for New Century Excellent Talents in University [NCET-07-0033]

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Mg/HA (10 wt.%, 20 wt.% and 30 wt.%) composites were prepared by pure magnesium and hydroxyapatite (HA) powders using powder metallurgy (PM) method. The microstructure, mechanical property, corrosion and cytotoxicity of these Mg/HA composites were studied, with the bulk pure magnesium as control. The results showed that the main constitutional phases of Mg/HA composites were simply alpha-Mg and HA. The HA particulates distributed uniformly in Mg matrix for Mg/10HA composite, and few HA clustering occasionally spread over the Mg/20HA composite, whereas severe agglomeration of HA particulates could be seen for Mg/30HA composite. The yield tensile strength of Mg/10HA composite increased compared with that of the as-extruded bulk pure magnesium, yet the yield tensile strength, ultimate tensile strength and ductility of Mg/HA composites decreased with the further increase of HA content. The corrosion rate of Mg/HA composites increased with the increment of HA content. The cytotoxicity tests indicated that Mg/10HA extract showed no toxicity to L-929 cells, whereas Mg/20HA and Mg/30HA composite extracts induced significantly reduced cell viability. (C) 2010 Elsevier B.V. All rights reserved.

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