Corrosion resistance, anticoagulant and antibacterial properties of surface-functionalized magnesium alloys

Impressive progress has been made on the development of magnesium alloys (Mg) implants in cardiovascular and orthopedic applications due to their good mechanical strength and biodegradable. In this paper, heparin and carboxymethyl chitosan were immobilized on alkali-treated Mg to improve the hemocompatibility and antibacterial activities. Electrochemical tests revealed that the surface modified Mg obviously improved the corrosion resistance. Additionally, the surface-functionalized Mg exhibited excellent antithrombotic and antibacterial activities. (C) 2018 Elsevier B.V. All rights reserved.