期刊
MATERIALS CHEMISTRY AND PHYSICS
卷 118, 期 1, 页码 99-104出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.matchemphys.2009.07.011
关键词
Titania; Silver; Plasma spray; Biological property; Antibacterial property
资金
- National Basic Research Fund [2005CB623901]
- National Natural Science Foundation of China [30700170]
- Shanghai Science and Technology RD Fund [07QH14016, 07JC14057, 0852nm03300, 08ZR1421600]
- SICCAS [SCX0606]
In this work. plasma sprayed nano-titania/silver coatings were deposited oil titanium substrates to obtain an implant material having excellent antibacterial property The surface characteristics of nano-titania/silver coatings were investigated by scanning electron microscopy, energy dispersive spectrometer. optical emission spectrometry and X-ray diffraction. The bioactivity of nano-titania/silver coatings was examined by simulated body fluid soaking test. The antibacterial activity against Escherichia colt was examined by bacterial counting method The cytocompatibility and in vitro osteotoxicity was evaluated by alamarBlue (TM) Assay using MG-63 osteoblasts The results showed that nano-titania/silver coatings still had good bioactivity Silver existed homogeneously in the nano-titania coating as silver oxide and metal silver, which ensured a sustained release of silver for 28 days. The loaded silver had no obvious osteotoxicity. while showed strong inhibition against the growth of Escherichia coli. (c) 2009 Elsevier B.V. All rights reserved
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