期刊
MARINE ENVIRONMENTAL RESEARCH
卷 91, 期 -, 页码 52-60出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.marenvres.2012.12.010
关键词
Environmental toxicology; Coastal waters; Eastern Sicily; Mytilus galloprovincialis; Digestive gland; Biomarker; Cytochrome; Glutathione S-transferase; Catalase
Biological effects of environmental pollution, mainly related to presence of PAHs, were assessed in mussels Mytilus galloprovincialis caged in Priolo, an anthropogenically-impacted area, and Vendicari, a reference site, both located along the eastern coastline of Sicily (Italy). PAHs concentration and histopathological changes were measured in digestive gland tissues. Expression of cytochrome P4504Y1 (CYP4Y1) and glutathione S-transferase (GST), indicative of xenobiotic detoxification, and activity of catalase (CAT) as oxidative stress index, were evaluated. The results show a direct correlation between the high concentrations of PAHs in digestive glands of mussels from Priolo and the significantly altered activity of phase I (P < 0.001) and phase II (P < 0.0001) biotransformation enzymes, along with increased levels of CAT activity (P < 0.05). These findings show the enhancement of the detoxification and antioxidant defense systems. The mussel caging approach and selected biomarkers demonstrated to be reliable for the assessment of environmental pollution effects on aquatic organisms. (C) 2013 Elsevier Ltd. All rights reserved.
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