期刊
MARINE DRUGS
卷 12, 期 12, 页码 5993-6002出版社
MDPI AG
DOI: 10.3390/md12125993
关键词
asperentin; endophytic fungus; crop pathogen; alpha-D-ribofuranose
资金
- National Natural Science Foundation of China [81422045, U1405223]
- Science and Technology Plan Project of Xiamen [3502Z20133010, 3502Z20123010]
- Fundamental Research Funds for the Central Universities of China [2011121030, 2013121032, 2010121092]
Three new asperentin-type compounds, 6-O-alpha-D-ribosylasperentin (1) and 6-O-alpha-D-ribosyl-8-O-methylasperentin (2) and 5-hydroxyl-6-O-methylasperentin (3), along with asperentin (4) and its known analogues (5-9), were isolated from a halotolerant Aspergillus sp. strain F00785, an endotrophic fungus from marine alga. Their structures were determined using extensive NMR and HRESIMS spectroscopic analysis, including the X-ray crystallographic data for the assignment of the absolute configurations of compound 9. Compound 4 exhibited highly potent inhibitory activity against crop pathogens, Colletotrichum gleosporioides Penz. and Colletotrichum gleosporioides (Penz.) Sacc.
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