期刊
MARINE DRUGS
卷 10, 期 11, 页码 2509-2518出版社
MDPI
DOI: 10.3390/md10112509
关键词
natural products; sponges; Axinellidae; pyrrole-imidazole alkaloids; taxon-specificity
资金
- EU [229893]
- MIUR
An exhaustive exploration into the metabolic content of the Mediterranean sponge Axinella-polypoides resulted in the isolation of the new betaine 5 and the new cyclonucleoside 8. The structures of the new metabolites were elucidated by spectroscopic methods assisted by computational methods. The analysis also provided evidence that the sponge does not elaborate pyrrole-imidazole alkaloids (PIAs) but, interestingly, it was shown to contain two already known cyclodipeptides, compounds 9 (verpacamide A) and 10.
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