期刊
MARINE DRUGS
卷 9, 期 11, 页码 2220-2235出版社
MDPI
DOI: 10.3390/md9112220
关键词
Laurencia viridis; squalene; polyethers; cytotoxic activity
资金
- EU [KBBE-3-245137]
- MICINN [CTQ2008-06754-C04-01, SAF2008-02251]
- ACISII [C2008000145, EXMAR]
- Red Tematica de Investigacion Cooperativa en Cancer [RD06/0020/1037]
- Instituto de Salud Carlos III
- Fondo Europeo de Desarrollo Regional of the European Union
- Junta de Castilla y Leon [CSI052A11-2]
- SEGAI-ULL
The red seaweed Laurencia viridis is a rich source of secondary metabolites derived from squalene. New polyethers, such as iubol (2), 22-hydroxy-15(28)-dehydrovenustatriol (3), 1,2-dehydropseudodehydrothyrsiferol (4), and secodehydrothyrsiferol (5) have been isolated and characterized from this alga. The structures were determined through the interpretation of NMR spectroscopic data and the relative configuration was proposed on the basis of NOESY spectrum and biogenetic considerations. All new compounds exhibited significant cytotoxic activity against a panel of cancer cell lines.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据