期刊
MARINE DRUGS
卷 8, 期 7, 页码 1962-1987出版社
MDPI AG
DOI: 10.3390/md8071962
关键词
chitosan derivatives; hypocholesterolemic; immunoenhancing; homeostasis; D-Glucosaminic Acid
资金
- National Nature Science Foundation of China (NSFC) [20571034, 20876068]
- State high-tech project [2007AA091603, 2007AA100401, 2006AA09Z444]
- 111project [B07029]
- [BA2009082]
- [SKLF-MB-200805]
- [PCSIRT0627]
Chitosan has received much attention as a functional biopolymer for diverse applications, especially in pharmaceutics and medicine. Our recent efforts focused on the chemical and biological modification of chitosan in order to increase its solubility in aqueous solutions and absorbability in the in vivo system, thus for a better use of chitosan. This review summarizes chitosan modification and its pharmaceutical/biomedical applications based on our achievements as well as the domestic and overseas developments: (1) enzymatic preparation of low molecular weight chitosans/chitooligosaccharides with their hypocholesterolemic and immuno-modulating effects; (2) the effects of chitin, chitosan and their derivatives on blood hemostasis; and (3) synthesis of a non-toxic ion ligand-D-Glucosaminic acid from Oxidation of D-Glucosamine for cancer and diabetes therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据