期刊
MARINE DRUGS
卷 8, 期 12, 页码 2976-2987出版社
MDPI
DOI: 10.3390/md8122976
关键词
lactones; sulfur compounds; pyrazines; bacterial communication; quorum-sensing; ketones; aromatic compounds; agar diffusion assay; terpenes
资金
- Deutsche Forschungsgemeinschaft
The antiproliferative activity of 52 volatile compounds released from bacteria was investigated in agar diffusion assays against medically important microorganisms and mouse fibroblasts. Furthermore, the activity of these compounds to interfere with the quorum-sensing-systems was tested with two different reporter strains. While some of the compounds specific to certain bacteria showed some activity in the antiproliferative assay, the compounds common to many bacteria were mostly inactive. In contrast, some of these compounds were active in the quorum-sensing-tests. gamma-Lactones showed a broad reactivity, while pyrazines seem to have only low intrinsic activity. A general discussion on the ecological importance of these findings is given.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据