期刊
MAGNETIC RESONANCE IN MEDICINE
卷 74, 期 5, 页码 1291-1305出版社
WILEY-BLACKWELL
DOI: 10.1002/mrm.25512
关键词
7 Tesla; cardiac MRI; respiration; breath-hold; pTX; spoke pulses; RF pulse design
资金
- National Institutes of Health [S10 RR26783, P41 EB015894, R21 EB009138, R01-EB006835, R01-EB007327]
- W. M. Keck Foundation
PurposeTwo-spoke parallel transmission (pTX) radiofrequency (RF) pulses have been demonstrated in cardiac MRI at 7T. However, current pulse designs rely on a single set of B-1(+)/B-0 maps that may not be valid for subsequent scans acquired at another phase of the respiration cycle because of organ displacement. Such mismatches may yield severe excitation profile degradation. MethodsB(1)(+)/B-0 maps were obtained, using 16 transmit channels at 7T, at three breath-hold positions: exhale, half-inhale, and inhale. Standard and robust RF pulses were designed using maps obtained at exhale only, and at multiple respiratory positions, respectively. Excitation patterns were analyzed for all positions using Bloch simulations. Flip-angle homogeneity was compared in vivo in cardiac CINE acquisitions. ResultsStandard one- and two-spoke pTX RF pulses are sensitive to breath-hold position, primarily due to B-1(+) alterations, with high dependency on excitation trajectory for two spokes. In vivo excitation inhomogeneity varied from nRMSE = 8.2% (exhale) up to 32.5% (inhale) with the standard design; much more stable results were obtained with the robust design with nRMSE = 9.1% (exhale) and 10.6% (inhale). ConclusionA new pTX RF pulse design robust against respiration induced variations of B-1(+)/B-0 maps is demonstrated and is expected to have a positive impact on cardiac MRI in breath-hold, free-breathing, and real-time acquisitions. Magn Reson Med 74:1291-1305, 2015. (c) 2014 Wiley Periodicals, Inc.
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