期刊
MAGNETIC RESONANCE IN MEDICINE
卷 68, 期 2, 页码 389-399出版社
WILEY
DOI: 10.1002/mrm.23228
关键词
prospective motion correction; navigator; brain morphometry; validation
资金
- Center for Functional Neuroimaging Technologies [P41RR14075]
- National Center for Research Resources (NCRR), National Institutes of Health
- NCRR [S10RR021110, S10RR023401]
- NIH [5R21EB008547, 5R21AA017410, 5R21DA026104, 5R01NS055754]
- Ellison Medical Foundation
- Medical Research Council [G0700796] Funding Source: researchfish
- MRC [G0700796] Funding Source: UKRI
We introduce a novel method of prospectively compensating for subject motion in neuroanatomical imaging. Short three-dimensional echo-planar imaging volumetric navigators are embedded in a long three-dimensional sequence, and the resulting image volumes are registered to provide an estimate of the subject's location in the scanner at a cost of less than 500 ms, similar to 1% change in contrast, and similar to 3% change in intensity. This time fits well into the existing gaps in sequences routinely used for neuroimaging, thus giving a motion-corrected sequence with no extra time required. We also demonstrate motion-driven selective reacquisition of k-space to further compensate for subject motion. We perform multiple validation experiments to evaluate accuracy, navigator impact on tissue intensity/contrast, and the improvement in final output. The complete system operates without adding additional hardware to the scanner and requires no external calibration, making it suitable for high-throughput environments. Magn Reson Med, 2012. (C) 2011 Wiley Periodicals, Inc.
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