期刊
MAGNETIC RESONANCE IN MEDICINE
卷 65, 期 5, 页码 1269-1277出版社
WILEY-BLACKWELL
DOI: 10.1002/mrm.22717
关键词
coronary MRA; 3D PR k-space sampling; 3D affine transform; respiratory motion correction
资金
- National Institute of Health [NIBIB EB002623, NHLBI HL38698]
- Siemens Medical Solutions USA Inc. Malvern, PA
- Captain and Mrs. Roberts Fellowship
The navigator gating and slice tracking approach currently used for respiratory motion compensation during free-breathing coronary magnetic resonance angiography (MRA) has low imaging efficiency (typically 30-50%), resulting in long imaging times. In this work, a novel respiratory motion correction technique with 100% scan efficiency was developed for free-breathing whole-heart coronary MRA. The navigator signal was used as a reference respiratory signal to segment the data into six bins. 3D projection reconstruction k-space sampling was used for data acquisition and enabled reconstruction of low resolution images within each respiratory bin. The motion between bins was estimated by image registration with a 3D affine transform. The data from the different respiratory bins was retrospectively combined after motion correction to produce the final image. The proposed method was compared with a traditional navigator gating approach in nine healthy subjects. The proposed technique acquired whole-heart coronary MRA with 1.0 mm(3) isotropic spatial resolution in a scan time of 6.8 +/- 0.9 min, compared with 16.2 +/- 2.8 min for the navigator gating approach. The image quality scores, and length, diameter and sharpness of the right coronary artery (RCA), left anterior descending coronary artery (LAD), and left circumflex coronary artery (LCX) were similar for both approaches (P > 0.05 for all), but the proposed technique reduced scan time by a factor of 2.5. Magn Reson Med 65:1269-1277, 2011. (c) 2011 Wiley-Liss, Inc.
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