A Respiratory Self-Gating Technique with 3D-Translation Compensation for Free-Breathing Whole-Heart Coronary MRA

Respiratory motion remains a major challenge for robust coronary MR angiography (MRA). Diaphragmatic navigator (NAV) suffers from indirect measurement of heart position. Respiratory self-gating (RSG) approaches improve motion detection only in the head-feet direction, leaving motion in the other two dimensions unaccounted for. The purpose of this study was to extend conventional RSG (1D RSG) to RSG capable of 3D motion detection (3D RSG) by acquiring additional RSG projections with transverse-motion-encoding gradients. Simulation and volunteer studies were conducted to validate the effectiveness of this new method. Preliminary comparison was performed between coronary artery images reconstructed from the same datasets using different motion correction methods. Our simulation illustrates that a proper motion-encoding gradient and derivation method enable accurate 3D motion detection. Results from whole-heart coronary MRA show that 3D RSG can further reduce motion artifacts as compared to NAV and 1D RSG and enables use of larger gating windows for faster coronary imaging. Magn Reson Med 62:731-738, 2009. (C) 2009 Wiley-Liss, Inc.