期刊
MAGNETIC RESONANCE IN MEDICINE
卷 59, 期 6, 页码 1355-1364出版社
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.21585
关键词
B-1(+) inhomogeneity mitigation; high field; RF pulse design; 3-D RF excitation; in vivo; sparse approximation
资金
- NCRR NIH HHS [P41 RR014075-086768, P41RR14075, P41 RR014075-098608, P41 RR014075, P41 RR014075-098604, P41 RR014075-086772] Funding Source: Medline
- NIBIB NIH HHS [R01 EB006847-02S1, 1R01EB006847, 1R01EB000790, R01 EB007942, R01 EB006847-01A2, 1R01EB007942, R01 EB000790, R01 EB006847-02, R01 EB007942-01A2, R01 EB006847] Funding Source: Medline
- NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR014075] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB000790, R01EB007942, R01EB006847] Funding Source: NIH RePORTER
A novel radio-frequency (RF) pulse design algorithm is presented that generates fast slice-selective excitation pulses that mitigate B-1(+) inhomogeneity present in the human brain at high field. The method is provided an estimate of the B-1(+) field in an axial slice of the brain and then optimizes the placement of sinc-like spokes in k(z) via an L-1-norm penalty on candidate (k(x), k(y)) locations; an RF pulse and gradients are then designed based on these weighted points. Mitigation pulses are designed and demonstrated at 7T in a head-shaped water phantom and the brain; in each case, the pulses mitigate a significantly non-uniform transmit profile and produce nearly uniform flip angles across the field of excitation (FOX). The main contribution of this work, the sparsity-enforced spoke placement and pulse design algorithm, is derived for conventional single-channel excitation systems and applied in the brain at 7T, but readily extends to lower field systems, nonbrain applications, and multichannel parallel excitation arrays.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据