Structural elucidation and NMR assignments of two new pyrrolosesquiterpenes from Streptomyces sp Hd7-21

Two new pyrrolosesquiterpenes were isolated from cultures of the soil actinomycete Streptomyces sp. Hd7-21. The structures of these compounds were elucidated by extensive spectroscopic analyses including MS and 1D and 2D NMR data. Their cytotoxic activity against a panel of human cancer cell lines were biologically evaluated. Copyright (c) 2013 John Wiley & Sons, Ltd.