期刊
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA
卷 18, 期 3, 页码 359-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mric.2010.08.014
关键词
Iron quantification; Magnetic resonance imaging; Hepatic iron overload; Quantitative biomarkers
资金
- NIDDK NIH HHS [R01 DK088925-03, R01 DK088925] Funding Source: Medline
Iron overload is the histologic hallmark of hereditary hemochromatosis and transfusional hemosiderosis but also may occur in chronic hepatopathies. This article provides an overview of iron deposition and diseases where liver iron overload is clinically relevant. Next, this article reviews why quantitative noninvasive biomarkers of liver iron would be beneficial. Finally, we describe current state-of-the-art methods for quantifying iron with MR imaging and review remaining challenges and unsolved problems.
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