期刊
MAGNETIC RESONANCE IMAGING
卷 26, 期 4, 页码 560-566出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mri.2007.10.007
关键词
magnetic resonance imaging; 7 T; cartilage morphology; trabecular bone structure; reproducibility
资金
- NIAMS NIH HHS [R01 AR046905, R01 AR046905-07] Funding Source: Medline
To assess the reproducibility of quantitative measurements of cartilage morphology and trabecular bone structure of the knee at 7 T, high-resolution sagittal spoiled gradient-echo images and high-resolution axial fully refocused steady-state free-precession (SSFP) images from six healthy volunteers were acquired with a 7-T scanner. The subjects were repositioned between repeated scans to test the reproducibility of the measurements. The reproducibility of each measurement was evaluated using the coefficient(s) of variation (CV). The computed CV were 1.13% and 1.55% for cartilage thickness and cartilage volume, respectively, and were 2.86%, 1.07%, 2.27% and 3.30% for apparent bone volume over total volume fraction (app.BV/TV), apparent trabecular number (app.Tb.N), apparent trabecular separation (app.Tb.Sp) and apparent trabecular thickness (app.Tb.Th), respectively. The results demonstrate that quantitative assessment of cartilage morphology and trabecular bone structure is reproducible at 7 T and motivates future musculoskeletal applications seeking the high-field strength's superior signal-to-noise ratio. (c) 2008 Elsevier Inc. All rights reserved.
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