4.3 Review

The translation of cell-based therapies: clinical landscape and manufacturing challenges

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

A potentially scalable method for the harvesting of hMSCs from microcarriers

Alvin W. Nienow et al.

BIOCHEMICAL ENGINEERING JOURNAL (2014)

Article Multidisciplinary Sciences

Oxygen Transport and Stem Cell Aggregation in Stirred-Suspension Bioreactor Cultures

Jincheng Wu et al.

PLOS ONE (2014)

Article Cell & Tissue Engineering

The global landscape of stem cell clinical trials

Matthew D. Li et al.

REGENERATIVE MEDICINE (2014)

Article Biotechnology & Applied Microbiology

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Alvin W. Nienow et al.

BIOCHEMICAL ENGINEERING JOURNAL (2013)

Article Biotechnology & Applied Microbiology

Evaluation of a novel pneumatic bioreactor system for culture of recombinant Chinese hamster ovary cells

Jae Choon Kim et al.

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2013)

Article Biotechnology & Applied Microbiology

Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor

Qasim A. Rafiq et al.

BIOTECHNOLOGY LETTERS (2013)

Review Cell & Tissue Engineering

MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation

Thomas J. Kean et al.

STEM CELLS INTERNATIONAL (2013)

Editorial Material Cell & Tissue Engineering

The Global Cell Therapy Industry Continues to Rise during the Second and Third Quarters of 2012

Chris Mason et al.

CELL STEM CELL (2012)

Review Cell & Tissue Engineering

The Promise and Perils of Stem Cell Therapeutics

George Q. Daley

CELL STEM CELL (2012)

Editorial Material Medicine, General & Internal

Human embryonic stem cells: early hints on safety and efficacy

Anthony Atala

LANCET (2012)

Article Medicine, General & Internal

Embryonic stem cell trials for macular degeneration: a preliminary report

Steven D. Schwartz et al.

LANCET (2012)

Article Multidisciplinary Sciences

Precision manufacturing for clinical-quality regenerative medicines

David J. Williams et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2012)

Editorial Material Cell & Tissue Engineering

A decade of cell therapy clinical trials (2000-2010)

Emily J. Culme-Seymour et al.

REGENERATIVE MEDICINE (2012)

Article Biochemical Research Methods

A single-use purification process for the production of a monoclonal antibody produced in a PER.C6 human cell line

Michael Kuczewski et al.

BIOTECHNOLOGY JOURNAL (2011)

Article Biochemical Research Methods

Insights into large-scale cell-culture reactors: II. Gas-phase mixing and CO2 stripping

Christian Sieblist et al.

BIOTECHNOLOGY JOURNAL (2011)

Review Medicine, General & Internal

Clinical trials for stem cell therapies

Alan Trounson et al.

BMC MEDICINE (2011)

Editorial Material Multidisciplinary Sciences

STEM CELLS The dark side of induced pluripotency

Martin F. Pera

NATURE (2011)

Article Medicine, General & Internal

The ClinicalTrials.gov Results Database - Update and Key Issues

Deborah A. Zarin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Engineering, Biomedical

Simultaneous expansion and harvest of hematopoietic stem cells and mesenchymal stem cells derived from umbilical cord blood

Song Kedong et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2010)

Article Medicine, General & Internal

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer.

Philip W. Kantoff et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Editorial Material Cell & Tissue Engineering

The Translation Cycle: round and round in cycles is the only way forward for regenerative medicine FOREWORD

Chris Mason et al.

REGENERATIVE MEDICINE (2010)

Editorial Material Cell & Tissue Engineering

Defeating stem cell tourism FOREWORD

Chris Mason et al.

REGENERATIVE MEDICINE (2010)

Editorial Material Cell & Tissue Engineering

Regenerative medicine cell therapies: numbers of units manufactured and patients treated between 1988 and 2010

Chris Mason et al.

REGENERATIVE MEDICINE (2010)

Review Cell & Tissue Engineering

Scalable Stirred-Suspension Bioreactor Culture of Human Pluripotent Stem Cells

Daniel E. Kehoe et al.

TISSUE ENGINEERING PART A (2010)

Article Biotechnology & Applied Microbiology

Automated, Scalable Culture of Human Embryonic Stem Cells in Feeder-Free Conditions

Rob J. Thomas et al.

BIOTECHNOLOGY AND BIOENGINEERING (2009)

Article Biotechnology & Applied Microbiology

Automated, serum-free production of CTX0E03: a therapeutic clinical grade human neural stem cell line

R. J. Thomas et al.

BIOTECHNOLOGY LETTERS (2009)

Editorial Material Cell & Tissue Engineering

Regen: the industry responsible for cell-based therapies FOREWORD

Chris Mason et al.

REGENERATIVE MEDICINE (2009)

Review Cell & Tissue Engineering

Assessing the value of autologous and allogeneic cells for regenerative medicine

Chris Mason et al.

REGENERATIVE MEDICINE (2009)

Article Cell & Tissue Engineering

Long-term microcarrier suspension cultures of human embryonic stem cells

Steve K. W. Oh et al.

STEM CELL RESEARCH (2009)

Review Cell & Tissue Engineering

The Systematic Production of Cells for Cell Therapies

Daniel C. Kirouac et al.

CELL STEM CELL (2008)

Article Biotechnology & Applied Microbiology

Manufacture of a human mesenchymal stem cell population using an automated cell culture platform

Robert James Thomas et al.

CYTOTECHNOLOGY (2007)

Article Biotechnology & Applied Microbiology

Evaluation of a novel Wave Bioreactor® cellbag for aerobic yeast cultivation

Mark Mikola et al.

BIOPROCESS AND BIOSYSTEMS ENGINEERING (2007)

Article Hematology

Multipotent adult progenitor cell isolation and culture procedures

April Breyer et al.

EXPERIMENTAL HEMATOLOGY (2006)

Article Biotechnology & Applied Microbiology

Reactor engineering in large scale animal cell culture

Alvin W. Nienow

CYTOTECHNOLOGY (2006)

Review Biotechnology & Applied Microbiology

Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals

M Butler

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)

Article Cell & Tissue Engineering

Tissue engineering: The end of the beginning

MJ Lysaght et al.

TISSUE ENGINEERING (2004)

Article Biotechnology & Applied Microbiology

In-situ microscopy: Online process monitoring of mammalian cell cultures

K Joeris et al.

CYTOTECHNOLOGY (2002)

Article Biotechnology & Applied Microbiology

Oxygen transfer in stirred bioreactors under animal cell culture conditions

C Langheinrich et al.

FOOD AND BIOPRODUCTS PROCESSING (2002)