期刊
MACROMOLECULAR RAPID COMMUNICATIONS
卷 32, 期 2, 页码 115-126出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.201000646
关键词
additives; advanced formulation; biomineralization; gene delivery; peptide polymer conjugate; polymer surfactants
资金
- DFG [BO1762/2]
- Max Planck Society
AB-block copolymers composed of a common synthetic polymer part and a monodisperse, monomer sequence-defined segment are considered belonging to the class of Precision Polymers. This overview summarizes the possibilities that arise from those precisely adjustable, functional polymers for materials science applications. The freely programmable monomer sequence of the discrete peptide segment allows adjusting properties such as interaction capabilities. This can be exploited to (i) specifically solubilize and transport low molecular weight drugs, (ii) to pack DNA, (iii) to direct crystallization, or (iv) to modulate adhesion behavior of cells on material surfaces. As evident from proteins, the room to improve the precision of synthetic macromolecules will offer plenty of opportunities.
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