期刊
MACROMOLECULAR RAPID COMMUNICATIONS
卷 29, 期 12-13, 页码 1156-1160出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.200700877
关键词
-
A highly efficient room-temperature synthetic route to bioconjugable polymeric nanoparticles in the 5-20 nm size range based on single-chain intramolecular click cycloaddition is described. It is illustrated by preparing single-chain cross-linked polymeric NPs from poly[MMA-co-(3-azidopropyl methacrylate)-co-(3-trimethylsilyl-propyn-1-yl methacrylate)] terpolymers using a one-pot procedure and a continuous addition technique. For polymeric NPs with an excess of azide groups, aminoacid/PMMA NPs were easily obtained by performing a second click reaction with propargyl glycine. This versatile and general method opens the way to the synthesis of other kinds of polymeric and bioconjugated NPs beyond those reported in this communication.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据