Thermo-Responsive Polyoxazolines with Widely Tuneable LCST

The click modification of statistical poly[2-(isopropyl/3-butenyl)-2-oxazoline] copolymers with omega-functionalized thiols can be used to generate a toolbox of thermo-responsive polymers. The cloud points of the polymers can be finely tuned over a wide range as a function of composition and hydrophilicity of the side chain (hydrocarbon, alcohol, carboxylic acid, etc.). Glycopolymers can be prepared exhibiting predictable cloud points in the whole accessible temperature range for water.