相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Field flow fractionation for assessing neonatal Fc receptor and Fcγ receptor binding to monoclonal antibodies in solution
Joey Pollastrini et al.
ANALYTICAL BIOCHEMISTRY (2011)
Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic Consequences
Weirong Wang et al.
DRUG METABOLISM AND DISPOSITION (2011)
Neonatal FcR Overexpression Boosts Humoral Immune Response in Transgenic Mice
Judit Cervenak et al.
JOURNAL OF IMMUNOLOGY (2011)
Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies
Weirong Wang et al.
MOLECULAR IMMUNOLOGY (2011)
FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen
Attila Vegh et al.
MABS (2011)
Efficient mucosal vaccination mediated by the neonatal Fc receptor
Lilin Ye et al.
NATURE BIOTECHNOLOGY (2011)
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells
Kristi Baker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner
Kyosuke Nakata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Prolonged activity of factor IX as a monomeric Fc fusion protein
Robert T. Peters et al.
BLOOD (2010)
Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys
Rong Deng et al.
DRUG METABOLISM AND DISPOSITION (2010)
Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding
Jan Terje Andersen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
X-ray Crystal Structures of Monomeric and Dimeric Peptide Inhibitors in Complex with the Human Neonatal Fc Receptor, FcRn
Adam R. Mezo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Neonatal Fc Receptor: From Immunity to Therapeutics
Timothy T. Kuo et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2010)
Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR
Takuo Suzuki et al.
JOURNAL OF IMMUNOLOGY (2010)
Enhanced antibody half-life improves in vivo activity
Jonathan Zalevsky et al.
NATURE BIOTECHNOLOGY (2010)
Tuning the serum persistence of human serum albumin domain III: diabody fusion proteins
Vania E. Kenanova et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2010)
Investigation of the Influence of FcRn on the Distribution of IgG to the Brain
Amit Garg et al.
AAPS JOURNAL (2009)
N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG
Timothy T. Kuo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Biodistribution of a Bispecific Single-chain Diabody and Its Half-life Extended Derivatives
Roland Stork et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity
Salit Tzaban et al.
JOURNAL OF CELL BIOLOGY (2009)
Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates
Yik Andy Yeung et al.
JOURNAL OF IMMUNOLOGY (2009)
Renal FcRn Reclaims Albumin but Facilitates Elimination of IgG
Menaka Sarav et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Structural characterization of a human Fc fragment engineered for extended serum half-life
Vaheh Oganesyan et al.
MOLECULAR IMMUNOLOGY (2009)
Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice
Hector Perez Montoyo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn
Hai Pan et al.
PROTEIN SCIENCE (2009)
Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn
Kristi Baker et al.
SEMINARS IN IMMUNOPATHOLOGY (2009)
The neonatal Fc receptor plays a crucial role in the metabolism of IgG in livestock animals
Judit Cervenak et al.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2009)
Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn
Adam R. Mezo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Infused Fc-tagged β-glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice
Jeffrey H. Grubb et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Podocytes use FcRn to clear IgG from the glomerular basement membrane
Shreeram Akilesh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Dependence of antibody-mediated presentation of antigen on FcRn
Shuo-Wang Qiao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mapping of the neonatal Fc receptor in the rodent eye
Hyuncheol Kim et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Over-expression of the bovine FcRn in the mammary gland results in increased IgG levels in both milk and serum of transgenic mice
Wei Lu et al.
IMMUNOLOGY (2007)
The neonatal Fc receptor (FcRn) expression in the human skin
Petru Cianga et al.
VIRCHOWS ARCHIV (2007)
Amelioration of experimental autoimmune myasthenia gravis in rats by neonatal FcR blockade
Liming Liu et al.
JOURNAL OF IMMUNOLOGY (2007)
Monoclonal antibody clearance -: Impact of modulating the interaction of IgG with the neonatal Fc receptor
Amita Datta-Mannan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Humanized IgG(1) variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates
Amita Datta-Mannan et al.
DRUG METABOLISM AND DISPOSITION (2007)
Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent
Mark S. Dennis et al.
CANCER RESEARCH (2007)
FcRn: the neonatal Fc receptor comes of age
Derry C. Roopenian et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
Stefka B. Petkova et al.
INTERNATIONAL IMMUNOLOGY (2006)
FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis
Gestur Vidarsson et al.
BLOOD (2006)
The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin
Jan Terje Andersen et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Pulmonary administration of therapeutic proteins using an immunoglobulin transport pathway
Alan J. Bitonti et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn)
William F. Dall'Acqua et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
Masaru Yoshida et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin
Allen Nguyen et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2006)
Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis
E Maidji et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life
B Gurbaxani et al.
MOLECULAR IMMUNOLOGY (2006)
Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces
JH Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
An engineered human IgG1 antibody with longer serum half-life
PR Hinton et al.
JOURNAL OF IMMUNOLOGY (2006)
Monomeric Fc fusions - Impact on pharmacokinetic and biological activity of protein therapeutics
Jennifer A. Dumont et al.
BIODRUGS (2006)
Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases
N Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels
C Vaccaro et al.
NATURE BIOTECHNOLOGY (2005)
Transport of IgG across the blood-luminal barrier of the male reproductive tract of the rat and the effect of estradiol administration on reabsorption of fluid and IgG by the epididymal ducts
RA Knee et al.
BIOLOGY OF REPRODUCTION (2005)
Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway
JA Dumont et al.
JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG (2005)
Oral and pulmonary delivery of FSH-Fc fusion proteins via neonatal Fc receptor-mediated transcytosis
SC Low et al.
HUMAN REPRODUCTION (2005)
Engineered human IgG antibodies with longer serum half-lives in primates
PR Hinton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Exocytosis of IgG as mediated by the receptor, FcRn: An analysis at the single-molecule level
RJ Ober et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway
AJ Bitonti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells
M Yoshida et al.
IMMUNITY (2004)
The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland
P Cianga et al.
HUMAN IMMUNOLOGY (2003)
Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G
JC Zhou et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan
C Chaudhury et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Increasing the affinity of a human IgG1, for the neonatal Fc receptor: Biological consequences
WF Dall'Acqua et al.
JOURNAL OF IMMUNOLOGY (2002)
FcRn-mediated transcytosis of immunoglobulin G in human renal proximal tubular epithelial cells
N Kobayashi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies
RJ Ober et al.
INTERNATIONAL IMMUNOLOGY (2001)
High resolution mapping of the binding site on human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and design of IgG1 variants with improved binding to the FcγR
RL Shields et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Convergent solutions to binding at a protein-protein interface
WL DeLano et al.
SCIENCE (2000)
分享论文
