相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule
D. Ouellette et al.
ANALYTICAL BIOCHEMISTRY (2010)
Antibodies to watch in 2010
Janice M. Reichert
MABS (2010)
Intrachain disulfide bond in the core hinge region of human IgG4
James W. Bloom et al.
PROTEIN SCIENCE (2010)
A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: A study by analytical ultracentrifugation
Barthelemy Demeule et al.
ANALYTICAL BIOCHEMISTRY (2009)
NUTS and BOLTS: Applications of fluorescence-detected sedimentation
Rachel R. Kroe et al.
ANALYTICAL BIOCHEMISTRY (2009)
Detection and Quantitation of IgG 1 Hinge Aspartate Isomerization A Rapid Degradation in Stressed Stability Studies
David M. Hambly et al.
ANALYTICAL CHEMISTRY (2009)
Challenges in monoclonal antibody-based therapies
Haritha Samaranayake et al.
ANNALS OF MEDICINE (2009)
Human antibody Fc deamidation in vivo
Y. Diana Liu et al.
BIOLOGICALS (2009)
Engineered therapeutic antibodies with improved effector functions
Tsuguo Kubota et al.
CANCER SCIENCE (2009)
Formulation and manufacturability of biologics
Steven J. Shire
CURRENT OPINION IN BIOTECHNOLOGY (2009)
The effect of Fc glycan forms on human IgG2 antibody clearance in humans
Xiaoyu Chen et al.
GLYCOBIOLOGY (2009)
Succinimide Formation at Asn 55 in the Complementarity Determining Region of a Recombinant Monoclonal Antibody IgG1 Heavy Chain
Boxu Yan et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors
Andrea Bertolotti-Ciarlet et al.
MOLECULAR IMMUNOLOGY (2009)
Human immunoglobulin allotypes Possible implications for immunogenicity
Roy Jefferis et al.
MABS (2009)
Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo
Aran F. Labrijn et al.
NATURE BIOTECHNOLOGY (2009)
Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn
Hai Pan et al.
PROTEIN SCIENCE (2009)
Structure and stability changes of human IgG1 Fc as a consequence of methionine oxidation
Dingjiang Liu et al.
BIOCHEMISTRY (2008)
Characterization of a complex glycoprotein whose variable metabolic clearance in humans is dependent on terminal N-acetylglucosamine content
Rodney Keck et al.
BIOLOGICALS (2008)
Effect of constant and variable domain glycosylation on pharmacokinetics of therapeutic antibodies in mice
Thomas A. Millward et al.
BIOLOGICALS (2008)
Human IgG2 antibodies display disulfide-mediated structural isoforms
Jette Wypych et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structural and functional characterization of disulfide isoforms of the human IgG2 subclass
Thomas M. Dillon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Human IgG2 Antibody Disulfide Rearrangement in Vivo
Y. Diana Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Removal of cysteinylation from an unpaired sulfhydryl in the variable region of a recombinant monoclonal IgG1 antibody improves homogeneity, stability, and biological activity
Douglas D. Banks et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Heterogeneity of monoclonal antibodies
Hongcheng Liu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function
Quin Zhou et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
Protein-thiol substitution or protein dethiolation by thiol/disulfide exchange reactions: The albumin model
Domenico Summa et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange
Marijn van der Neut Kolfschoten et al.
SCIENCE (2007)
Serum and plasma proteomics
Haleem J. Issaq et al.
CHEMICAL REVIEWS (2007)
Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Andrew J. S. Jones et al.
GLYCOBIOLOGY (2007)
Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody
Chris Churnsae et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
Altered immunogenicity of isoaspartate containing proteins
Hester A. Doyle et al.
AUTOIMMUNITY (2007)
Evaluation of the iCE280 Analyzer as a potential high-throughput tool for formulation development
Ning Li et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2007)
Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types
Yutaka Kanda et al.
GLYCOBIOLOGY (2007)
Isoaspartyl post-translational modification triggers anti-tumor T and B lymphocyte immunity
Hester A. Doyle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Analytical ultracentrifugation for association and assembly the study of protein
Geoffrey J. Howlett et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2006)
Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature
Hongcheng Liu et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2006)
Proteome analysis of human plasma and amniotic fluid by Off-Gel™ isoelectric focusing followed by nano-LC-MS/MS
PE Michel et al.
ELECTROPHORESIS (2006)
Impact of variable domain glycosylation on antibody clearance: An LC/MS characterization
LH Huang et al.
ANALYTICAL BIOCHEMISTRY (2006)
Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed
WB Chaderjian et al.
BIOTECHNOLOGY PROGRESS (2005)
Glycosylation of recombinant antibody therapeutics
R Jefferis
BIOTECHNOLOGY PROGRESS (2005)
Identification and characterization of deamidation sites in the conserved regions of human Immunoglobulin Gamma antibodies
D Chelius et al.
ANALYTICAL CHEMISTRY (2005)
Structural characterization of a recombinant monoclonal antibody by electrospray time-of-flight mass spectrometry
LT Wang et al.
PHARMACEUTICAL RESEARCH (2005)
The therapeutic antibodies market to 2008
AK Pavlou et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2005)
In vivo deamidation characterization of monoclonal antibody by LC/MS/MS
LH Huang et al.
ANALYTICAL CHEMISTRY (2005)
Monoclonal antibody successes in the clinic
JM Reichert et al.
NATURE BIOTECHNOLOGY (2005)
The human plasma proteome - A nonredundant list developed by combination of four separate sources
NL Anderson et al.
MOLECULAR & CELLULAR PROTEOMICS (2004)
Human antibody - Fc receptor interactions illuminated by crystal structures
JM Woof et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Structure-immunogenicity relationships of therapeutic proteins
S Hermeling et al.
PHARMACEUTICAL RESEARCH (2004)
Membrane proteins with immunoglobulin-like domains - a master superfamily of interaction molecules
AN Barclay
SEMINARS IN IMMUNOLOGY (2003)
The human serum proteome: Display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins
R Pieper et al.
PROTEOMICS (2003)
Alteration in the redox state of plasma in heart-transplant patients with moderate hyperhomocysteinemia
D Di Giuseppe et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2003)
The human plasma proteome - History, character, and diagnostic prospects
NL Anderson et al.
MOLECULAR & CELLULAR PROTEOMICS (2002)
Plasma cystine concentration and redox state in aging and physical exercise
W Hildebrandt et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2002)
Protein deamidation
NE Robinson
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Mannose receptor-mediated regulation of serum glycoprotein homeostasis
SJ Lee et al.
SCIENCE (2002)
Deamidation of human proteins
NE Robinson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex:: Mechanism of pH-dependent binding
WL Martin et al.
MOLECULAR CELL (2001)
Identification of multiple sources of charge heterogeneity in a recombinant antibody
RJ Harris et al.
JOURNAL OF CHROMATOGRAPHY B (2001)
High resolution mapping of the binding site on human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and design of IgG1 variants with improved binding to the FcγR
RL Shields et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Molecular clocks
NE Robinson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The inter-heavy chain disulfide bonds of IgG4 are in equilibrium with intra-chain disulfide bonds
J Schuurman et al.
MOLECULAR IMMUNOLOGY (2001)
Blood glutathione and cysteine changes in cardiovascular disease
BJ Mills et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2000)
分享论文
