期刊
LWT-FOOD SCIENCE AND TECHNOLOGY
卷 49, 期 1, 页码 1-7出版社
ELSEVIER
DOI: 10.1016/j.lwt.2012.04.009
关键词
Antioxidant; Anti-proliferative; Cyclooxygenase-2 (COX-2); Drying; Melissa officinalis L.
资金
- Chun Shan Medical University, Taichung, Taiwan [CSMU-96-OM-B-005, CSMU-96-OM-A-088]
Antioxidant, anti-proliferative and cyclooxygenase-2 (COX-2) inhibitory activities of ethanolic extracts from freeze (EF) and hot air (EH) dried lemon balm (Melissa officinalis L.) leaves were evaluated. Phytochemical contents in the extracts were also determined. Hot air drying significantly lowered phytochemical contents and biological activities of the extract of lemon balm leaves as compared with freeze drying. EF had higher levels of phenols, phenolic acids, flavonoids, proanthocyanidins, ascorbic acid and gamma-tocopherol than EH. Rosmarinic acid was the major compound and hesperetin was the highest level of flavonoid in the extracts. EF also presented higher antioxidant (beta-carotene bleaching inhibition, scavenging 2, 2-diphenyl-1-picrylhydrazyl radicals, reducing power and Trolox equivalent antioxidant capacity), anti-proliferative (proliferative inhibition for Hep G2, KB and TSGH 9201 human cancer cells) and COX-2 (induced by 12-O-teradecanoylphorbol-13-acetate in KB cells) suppressing activities than EH. The ethanolic extracts of lemon balm leaves, especially EF, may have the potential for cancer chemoprevention. (C) 2012 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据