期刊
LUMINESCENCE
卷 26, 期 2, 页码 77-85出版社
WILEY
DOI: 10.1002/bio.1279
关键词
electrochemiluminescence; tris(2,2 '-bipyridyl)ruthenium (II); applications
资金
- National Natural Science Foundation of China [20675078, 20735003, 90713022]
- 973 Project [2009CB930100, 2010CB933600]
- Chinese Academy of Sciences [KJCX2 YW HO9]
Electrochemiluminescence (ECL) of tris(2,2`-bipyridyl) ruthenium(II) [Ru(bpy)(3)(2+)] is an active research area and includes the synthesis of ECL-active materials, mechanistic studies and broad applications. Extensive research has been focused on this area, due to its scientific and practical importance. In this mini-review we focus on the bio-related applications of ECL. After a brief introduction to Ru(bpy)(3)(2+) ECL and its mechanisms, its application in constructing an effective bioassay is discussed in detail. Three types of ECL assay are covered: DNA, immunoassay and functional nucleic acid sensors. Finally, future directions for these assays are discussed. Copyright (c) 2011 John Wiley & Sons, Ltd.
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